Jim Levenstein (Jason Biggs) and his wife Michelle (Alyson Hannigan) head back to East Great Falls to attend their 13-year high school reunion in the company of Oz (Chris Klein), who is now a minor TV star, house husband Kevin (Thomas Ian Nicholas) and eternal wanderer Finch (Eddie Kaye Thomas).

Meanwhile, Stifler (Seann William Scott) is up to his puerile tricks. The arrival of Heather (Mena Suvari) and her cardiologist beau (Jay Harrington) piques Oz’s jealousy.