Ten crowd members were arrested as 5,000 police officers created a ring of steel around the royal wedding.
The suspects are being questioned for a variety of offences, including breach of the peace, handling stolen goods, assault and possessing an offensive weapon, thought to be a knife.
An abandoned car found in Westminster was inspected and cleared by specialist officers before the ceremony got under way. The arrests were made "within and outside the event footprint", Scotland Yard said.
More than 90 people were banned from the City of Westminster under bail conditions as part of pre-emptive efforts during the biggest police security operation in a generation.
Crowds along the streets surrounding the abbey were separated from the road along which the royal couple will travel by two sets of barriers several feet apart.
Officers stood at regular intervals along the route, many enjoying jokes with the well-wishers. Westminster Tube station was closed to prevent overcrowding, Transport for London said.
A total of 24 people suspected of planning disruption were arrested on Thursday.
It emerged that known anarchist Charlie Veitch is being held by officers in Cambridgeshire, suspected of planning a rally in Soho Square. He was arrested by Scotland Yard officers last night after posting on the internet that he was plotting disruption.
A Scotland Yard spokesman said he remained in custody after being questioned on suspicion of "conspiracy to cause a public nuisance and breach of the peace".
Another 20 suspected anarchists were banned from getting near the wedding as they were bailed after being arrested as part of a string of raids on squats across London on Thursday.